KalVista Advances Oral HAE Treatment with Key Regulatory Steps KalVista Pharmaceuticals is progressing with its investigational oral therapy, sebetralstat, for hereditary angioedema (HAE). The company has submitted regulatory applications across seven global regions, including the U.S. and Europe. If approved, sebetralstat could become the first oral on-demand HAE treatment, with an FDA decision expected by June 2025.12